- [Explore ](https://reasons.org/explore) - - Publication - - Disorders of Sexual Development  Publication Disorders of Sexual Development ===============================  by **Ryan Matthews** June 4, 2025 Advocates of transgenderism often present disorders of sexual development (DSDs) as evidence that there are sexes other than male and female, and that the traditional understanding of the sexes should be overturned in favor of more progressive approaches to human sexuality. This important cultural debate is obscured by the imprecise terminology used when discussing these disorders as well as their medical complexity. To clarify the topic and make it more accessible to a general readership, this paper defines and discusses important disorders such as Congenital Adrenal Hyperplasia (CAH), Androgen Insensitivity Syndrome (AIS), 5α-Reductase Type II Deficiency (5ARD), and Ovotesticular Syndrome (OT), as well as less relevant, but oft-cited conditions, such as de la Chapelle Syndrome, Swyer Syndrome, Mayer-Rokitansky-Küster-Hauser syndrome (MRKH), vaginal agenesis, undescended testes, Turner syndrome, and Klinefelter syndrome. Historical cases of individuals with DSDs are also discussed. Finally, the paper presents the prevalence of these conditions and their relevance to discussions of transsexualism. if(window.DEARPDF && window.DEARPDF.parseElements){window.DEARPDF.parseElements();}      [  ](https://reasons.org/explore/publications/facts-for-faith/after-death-i-d-will-i-still-be-me "After Death I.D.—Will I Still Be Me?")##### After Death I.D.—Will I Still Be Me? Most Christians are convinced that people will know each other in heaven. This belief brings great comfort to believers as they watch loved ones... Logic & Reason [  ](https://reasons.org/explore/publications/articles/a-review-of-sam-harris-the-moral-landscape-how-science-can-determine-human-values-part-2-of-3 "A Review of Sam Harris’ The Moral Landscape: How Science Can Determine Human Values, Part 2 (of 3)")##### A Review of Sam Harris’ The Moral Landscape: How Science Can Determine Human Values, Part 2 (of 3) Today continues my three-part review of atheist Sam Harris’ new book, The Moral Landscape: How Science Can Determine Human Values. (See part 1 here). [  ](https://reasons.org/explore/publications/facts-for-faith/climatology-reveals-creation-clues "Climatology Reveals Creation Clues")##### Climatology Reveals Creation Clues By day, climatologist Kevin Birdwell seeks answers to mysteries of human history via climatological records. By night, he uses that research to enhance his... Geology & Earth