In a bold and timely endeavor, this groundbreaking work ventures into the uncharted territories of human nature, synthesizing insights from philosophy of religion, anthropology, and philosophy of mind to forge a comprehensive and systematic theology of human persons. Drawing inspiration from the rich legacy of Cartesian thought, the author crafts a meticulous and compelling case for a substance dualism model, carefully calibrating it with scriptural passages and theological texts to illuminate the most essential Christian doctrines. By reviving the dormant resources of Cartesianism and addressing its common criticisms, this project offers a provocative and refreshing alternative to materialist ontology, reinvigorating the quest for a deeper understanding of what it means to be human.