When Charles Darwin penned the final sentence of The Origin of Species, he was left with a nagging enigma - a single, unexplained phenomenon that threatened to upend his groundbreaking theory. The "Cambrian explosion," a sudden and inexplicable appearance of diverse animal life in the fossil record, defied explanation. Despite the passage of time, this mystery has only deepened, as the anticipated ancestors of these ancient creatures have failed to materialize, and our understanding of the intricate biological machinery required to construct life forms has grown. In Darwin's Doubt, Stephen C. Meyer masterfully unravels the tangled threads of this enigma, presenting a compelling case that the origins of the complex biological information encoded in DNA, as well as the other baffling aspects of the Cambrian event, are more convincingly attributed to intelligent design rather than the unguided forces of evolution. Building upon the arguments presented in his earlier work, Signature in the Cell, Meyer's meticulous analysis sheds new light on the most profound and enduring mystery of the natural world.